Pylera (Bismuth Subcitrate Potassium / Metronidazole / Tetracycline Hydrochloride)
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Bismuth Subcitrate Potassium / Metronidazole / Tetracycline Hydrochloride Information
(lan soe' pra zole) (kla rith' roe mye sin) (a mox i sil' in)
Before taking lansoprazole, clarithromycin, and amoxicillin,
- tell your doctor and pharmacist if you are allergic to any antibiotics, including amoxicillin, azithromycin (Zithromax, Zmax), clarithromycin (Biaxin), erythromycin (E.E.S. 400, others), and penicillin; lansoprazole (Prevacid); any other medications; or any of the ingredients in amoxicillin tablets, clarithromycin capsules, or lansoprazole capsules. Ask your pharmacist for a list of the ingredients.
- tell your doctor if you are taking any of the following medications: cisapride (Propulsid) (not available in the U.S.), dihydroergotamine (D.H.E, Migranal), ergotamine (Ergomar, in Cafergot, in Migergot), pimozide (Orap), astemizole (Hismanal) (not available in the U.S.) or terfenadine (Seldane) (not available in the U.S.). Your doctor will probably tell you not to take lansoprazole, clarithromycin, and amoxicillin if you are taking one or more of these medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: other antibiotics such as ampicillin; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); bromocriptine (Cycloset, Parlodel); carbamazepine (Carbatrol, Epitol, Equetro,Tegretol, Teril); certain cholesterol-lowering medications including lovastatin (Advicor, Altoprev) and simvastatin (Zocor, in Simcor, in Vytorin); cilostazol (Pletal); colchicine (Colcrys, in Col-probenecid); cyclosporine (Gengraf, Neoral, Sandimmune); certain benzodiazepines including alprazolam (Niravam, Xanax), midazolam, and triazolam (Halcion); digoxin (Lanoxin); disopyramide (Norpace); fluconazole (Diflucan); iron supplements; ketoconazole (Nizoral); certain medications for HIV such as atazanavir Reyataz), ritonavir (Norvir, in Kaletra) and zidovudine (Retrovir, in Trizivir, in Combivir); methylprednisolone (Medrol); phenytoin (Dilantin, Phenytek); probenecid (Probalan, in Col-probenecid); quinidine (in Nuedexta); rifabutin (Mycobutin); sildenafil (Revatio, Viagra); tacrolimus (Astagraf XL, Prograf); theophylline (Theo 24, Theochron, Uniphyl, others),and valproate (Depacon). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking sucralfate (Carafate), take it 30 minutes after you take lansoprazole, clarithromycin, and amoxicillin.
- tell your doctor if you have or have ever had asthma, allergies, hives, hay fever, myasthenia gravis (a disease that causes muscle weakness); or kidney or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant or are breast-feeding. If you become pregnant while taking these medications, call your doctor.
- if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking lansoprazole, clarithromycin, and amoxicillin.
- stomach pain or cramps
- change in ability to taste food
- blistering or peeling skin
- swelling of the face, eyes, lips, tongue, arms, or legs
- difficulty breathing or swallowing
- sore throat, fever, chills, and other signs of infection
- watery or bloody diarrhea with or without stomach pain that occurs during your treatment or for up to 2 months afterward